Buffalo spleen may be the most frequently used organ in the animal. Nutritionally the spleen is high in iron, packed with protein, and low in fat, facts that are commonly overlooked when compared to roasts and steaks. The spleen is an edible organ that adds variety to the menu in a number of different dishes, casseroles, and appetizers. There is an amazing number of recipes on the Internet for preparing this very economical organ. Check it out. U.S. raised grass-fed buffalo.