As folks age one of their greater concerns is Cognitive Decline. Most nutritionists, medical professionals, and the media pretty well tell us that getting forgetful is a normal aging process. If it advances to Alzheimer's Disease (AD), well, you’re basically sunk. AI summarized the official word this way: “Alzheimer's disease is a progressive brain disorder that leads to memory loss, thinking difficulties, and changes in behavior. There is currently no cure, but treatments can help manage symptoms and improve quality of life.”

Of course the pharmaceutical industry has some drugs (like Donepezil and Rivastigmine) and newer treatments like Lecanemab and Donanemab they claim may help manage symptoms and slow the progression of the disease. The medical community has already spent billions on AD and has not yet developed a treatment protocol. That’s because they mostly focus on single pathways. Targeting one pathway can show change, but in human studies, these limited approaches do not work.

Based on this concept, in September 2014 Dale E. Bredesen, MD released a paper titled Reversal of cognitive decline: A novel therapeutic program. It’s an open access article available online. Dr. Bredesen is an expert in the mechanisms of neurodegenerative diseases such as AD. He is associated with both the Mary S. Easton Center for Alzheimer’s Disease Research, Department of Neurology, University of California and the Buck Institute for Research on Aging.

Studies suggesting AD is analogous to chronic illnesses like cancer, osteoporosis, and atherosclerosis inspired Dr. Bredesen to recruit ten AD patients for a metabolical approach that addressed multiple modalities. His approach addressed diet, supplements, sleep, exercise, and meditation. Nine of his ten participants showed marked improvement within three to six months.

The recommended diet requires a balanced Omega-6 (n6) and Omega-3 (n3) essential fatty acid ratio of 1:1, grass-fed meats, wild-caught seafood, n3 poultry, n3 pork, and dark green vegetables. It eliminates high glycemic foods, grains, seeds, processed foods, and most nuts.

Other recommendations include 30 minutes of exercise 4-5 days week, eight hours of sleep per night, daily meditation, fasting 12 hours between dinner and breakfast, optimized oral hygiene, and a list of supplements starting with two teaspoons a day of quality fish oil. All of the recommended supplements occur naturally in a combination of grass-fed meats, seafood, poultry, and dark green vegetables.

Numerous supplements were also prescribed because it was expected that most patients would not follow every single step of the protocol. Thus the supplements improved the odds because if enough steps were followed the minimum threshold would be exceeded, resulting in improvements.

And so it was. For more information about the supplements download Dr. Bredesen report “Reversal of Cognitive Decline: a Novel Therapeutic Program.”

Download PDF Here

Dale E. Bredesen, M.D. Pacific Neuroscience Institute and the Chief Scientific Officer at Apollo Health.

https://www.pacificneuroscienceinstitute.org/people/dale-bredesen/

https://www.apollohealthco.com/dr-bredesen/